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Osteosarcoma: prognosis plateau warrants retinoblastoma pathway targeted therapy
Osteosarcoma (OS) is the most common primary bone cancer in children and adolescents, affecting ~560 young patients in the United States annually. The term OS describes a diverse array of subtypes with varying prognoses, but the majority of tumors are high grade and aggressive. Perhaps because the t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657420/ https://www.ncbi.nlm.nih.gov/pubmed/29263893 http://dx.doi.org/10.1038/sigtrans.2016.1 |