Uncoupling of dynamin polymerization and GTPase activity revealed by the conformation-specific nanobody dynab

Dynamin is a large GTPase that forms a helical collar at the neck of endocytic pits, and catalyzes membrane fission (Schmid and Frolov, 2011; Ferguson and De Camilli, 2012). Dynamin fission reaction is strictly dependent on GTP hydrolysis, but how fission is mediated is still debated (Antonny et al....

Descripción completa

Detalles Bibliográficos
Autores principales: Galli, Valentina, Sebastian, Rafael, Moutel, Sandrine, Ecard, Jason, Perez, Franck, Roux, Aurélien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658065/
https://www.ncbi.nlm.nih.gov/pubmed/29022874
http://dx.doi.org/10.7554/eLife.25197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658065/
https://www.ncbi.nlm.nih.gov/pubmed/29022874
http://dx.doi.org/10.7554/eLife.25197

Ejemplares similares