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Parallel mapping with site-directed hydroxyl radicals and micrococcal nuclease reveals structural features of positioned nucleosomes in vivo

Micrococcal nuclease (MNase) has been widely used for analyses of nucleosome locations in many organisms. However, due to its sequence preference, the interpretations of the positions and occupancies of nucleosomes using MNase have remained controversial. Next-generation sequencing (NGS) has also be...

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Detalles Bibliográficos
Autores principales: Fuse, Tomohiro, Katsumata, Koji, Morohoshi, Koya, Mukai, Yukio, Ichikawa, Yuichi, Kurumizaka, Hitoshi, Yanagida, Akio, Urano, Takeshi, Kato, Hiroaki, Shimizu, Mitsuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658119/
https://www.ncbi.nlm.nih.gov/pubmed/29073207
http://dx.doi.org/10.1371/journal.pone.0186974