MKP-1 suppresses PARP-1 degradation to mediate cisplatin resistance

Understanding the mechanisms of platinum compound resistance, including cisplatin resistance, has important implications for improving cancer treatments. Previous studies identified a potential role for mitogen-activated protein kinase phosphatase-1 (MKP-1) in cisplatin resistance. This work focuses...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Juan, Kho, Dhonghyo, Zhou, Jun-Ying, Davis, Roger J, Wu, Gen Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658239/
https://www.ncbi.nlm.nih.gov/pubmed/28650468
http://dx.doi.org/10.1038/onc.2017.197

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658239/
https://www.ncbi.nlm.nih.gov/pubmed/28650468
http://dx.doi.org/10.1038/onc.2017.197

Ejemplares similares