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MKP-1 suppresses PARP-1 degradation to mediate cisplatin resistance

Understanding the mechanisms of platinum compound resistance, including cisplatin resistance, has important implications for improving cancer treatments. Previous studies identified a potential role for mitogen-activated protein kinase phosphatase-1 (MKP-1) in cisplatin resistance. This work focuses...

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Detalles Bibliográficos
Autores principales:	Wang, Juan, Kho, Dhonghyo, Zhou, Jun-Ying, Davis, Roger J, Wu, Gen Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658239/ https://www.ncbi.nlm.nih.gov/pubmed/28650468 http://dx.doi.org/10.1038/onc.2017.197

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