Studying the Progression of Amyloid Pathology and Its Therapy Using Translational Longitudinal Model of Accumulation and Distribution of Amyloid Beta

Long‐term effects of amyloid targeted therapy can be studied using a mechanistic translational model of amyloid beta (Aβ) distribution and aggregation calibrated on published data in mouse and human species. Alzheimer disease (AD) pathology is modeled utilizing age‐dependent pathological evolution f...

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Detalles Bibliográficos
Autores principales: Karelina, Tatiana, Demin, Oleg, Duvvuri, Sridhar, Nicholas, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658285/
https://www.ncbi.nlm.nih.gov/pubmed/28913897
http://dx.doi.org/10.1002/psp4.12249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658285/
https://www.ncbi.nlm.nih.gov/pubmed/28913897
http://dx.doi.org/10.1002/psp4.12249

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