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Association between AIRE gene polymorphism and rheumatoid arthritis: a systematic review and meta-analysis of case-control studies
Autoimmune regulator (AIRE) is a transcription factor that functions as a novel player in immunological investigations. In the thymus, it has a pivotal role in the negative selection of naive T-cells during central tolerance. Experimental studies have shown that single nucleotide polymorphism (SNP)...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658331/ https://www.ncbi.nlm.nih.gov/pubmed/29074995 http://dx.doi.org/10.1038/s41598-017-14375-z |