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Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms
Early-life stress, including maternal separation (MS), increases the vulnerability to develop mood disorders later in life, but the underlying mechanisms remain elusive. We report that MS promotes depressive-like symptoms in mice at a mature stage of life. Along with this behavioral phenotype, MS dr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658350/ https://www.ncbi.nlm.nih.gov/pubmed/29074844 http://dx.doi.org/10.1038/s41467-017-01192-1 |