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Epidermal SIRT1 regulates inflammation, cell migration, and wound healing

Sirtuins (SIRT1-7) are NAD-dependent proteins with the enzymatic activity of deacetylases and ADP ribosyltransferases. SIRT1 is the proto member of the proteins in the mammalian sirtuin family and plays multiple roles in aging and disease. Using mice with epidermis-specific SIRT1 deletion, we show t...

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Detalles Bibliográficos
Autores principales: Qiang, Lei, Sample, Ashley, Liu, Han, Wu, Xiaoyang, He, Yu-Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658409/
https://www.ncbi.nlm.nih.gov/pubmed/29074993
http://dx.doi.org/10.1038/s41598-017-14371-3