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Gag P2/NC and pol genetic diversity, polymorphism, and drug resistance mutations in HIV-1 CRF02_AG- and non-CRF02_AG-infected patients in Yaoundé, Cameroon

In HIV-1 subtype-B, specific mutations in Gag cleavage sites (CS) are associated with treatment failure, with limited knowledge among non-B subtypes. We analyzed non-B HIV-1 gag and pol (protease/reverse-transcriptase) sequences from Cameroonians for drug resistance mutations (DRMs) in the gag P2/NC...

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Detalles Bibliográficos
Autores principales: Teto, Georges, Tagny, Claude T., Mbanya, Dora, Fonsah, Julius Y., Fokam, Joseph, Nchindap, Emilienne, Kenmogne, Léopoldine, Njamnshi, Alfred K., Kanmogne, Georgette D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658410/
https://www.ncbi.nlm.nih.gov/pubmed/29074854
http://dx.doi.org/10.1038/s41598-017-14095-4