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Host blood RNA signatures predict the outcome of tuberculosis treatment

Biomarkers for tuberculosis treatment outcome will assist in guiding individualized treatment and evaluation of new therapies. To identify candidate biomarkers, RNA sequencing of whole blood from a well-characterized TB treatment cohort was performed. Application of a validated transcriptional corre...

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Detalles Bibliográficos
Autores principales: Thompson, Ethan G., Du, Ying, Malherbe, Stephanus T., Shankar, Smitha, Braun, Jackie, Valvo, Joe, Ronacher, Katharina, Tromp, Gerard, Tabb, David L., Alland, David, Shenai, Shubhada, Via, Laura E., Warwick, James, Aderem, Alan, Scriba, Thomas J., Winter, Jill, Walzl, Gerhard, Zak, Daniel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Churchill Livingstone 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658513/
https://www.ncbi.nlm.nih.gov/pubmed/29050771
http://dx.doi.org/10.1016/j.tube.2017.08.004