Deficient autophagy in microglia impairs synaptic pruning and causes social behavioral defects

Autism spectrum disorders (ASDs) are neurodevelopmental disorders caused by various genetic and environmental factors that result in synaptic abnormalities. ASD development is suggested to involve microglia, which have a role in synaptic refinement during development. Autophagy and related pathways...

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Detalles Bibliográficos
Autores principales: Kim, H-J, Cho, M-H, Shim, W H, Kim, J K, Jeon, E-Y, Kim, D-H, Yoon, S-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658669/
https://www.ncbi.nlm.nih.gov/pubmed/27400854
http://dx.doi.org/10.1038/mp.2016.103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658669/
https://www.ncbi.nlm.nih.gov/pubmed/27400854
http://dx.doi.org/10.1038/mp.2016.103

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