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RNA polymerase II primes Polycomb‐repressed developmental genes throughout terminal neuronal differentiation

Polycomb repression in mouse embryonic stem cells (ESCs) is tightly associated with promoter co‐occupancy of RNA polymerase II (RNAPII) which is thought to prime genes for activation during early development. However, it is unknown whether RNAPII poising is a general feature of Polycomb repression,...

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Detalles Bibliográficos
Autores principales: Ferrai, Carmelo, Torlai Triglia, Elena, Risner‐Janiczek, Jessica R, Rito, Tiago, Rackham, Owen JL, de Santiago, Inês, Kukalev, Alexander, Nicodemi, Mario, Akalin, Altuna, Li, Meng, Ungless, Mark A, Pombo, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658700/
https://www.ncbi.nlm.nih.gov/pubmed/29038337
http://dx.doi.org/10.15252/msb.20177754