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In situ genotyping of a pooled strain library after characterizing complex phenotypes

In this work, we present a proof‐of‐principle experiment that extends advanced live cell microscopy to the scale of pool‐generated strain libraries. We achieve this by identifying the genotypes for individual cells in situ after a detailed characterization of the phenotype. The principle is demonstr...

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Detalles Bibliográficos
Autores principales: Lawson, Michael J, Camsund, Daniel, Larsson, Jimmy, Baltekin, Özden, Fange, David, Elf, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658705/
https://www.ncbi.nlm.nih.gov/pubmed/29042431
http://dx.doi.org/10.15252/msb.20177951