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Clickable Substrate Mimics Enable Imaging of Phospholipase D Activity

[Image: see text] Chemical imaging techniques have played instrumental roles in dissecting the spatiotemporal regulation of signal transduction pathways. Phospholipase D (PLD) enzymes affect cell signaling by producing the pleiotropic lipid second messenger phosphatidic acid via hydrolysis of phosph...

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Detalles Bibliográficos
Autores principales: Bumpus, Timothy W., Baskin, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658752/
https://www.ncbi.nlm.nih.gov/pubmed/29104923
http://dx.doi.org/10.1021/acscentsci.7b00222