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Molecular analysis of pyrazinamide resistance in Mycobacterium tuberculosis in Vietnam highlights the high rate of pyrazinamide resistance-associated mutations in clinical isolates

Pyrazinamide (PZA) is a key antibiotic in current anti-tuberculosis regimens. Although the WHO has stressed the urgent need to obtain data on PZA resistance, in high tuberculosis burden countries, little is known about the level of PZA resistance, the genetic basis of such resistance or its link wit...

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Detalles Bibliográficos
Autores principales: Huy, Nguyen Quang, Lucie, Contamin, Hoa, Tran Thi Thanh, Hung, Nguyen Van, Lan, Nguyen Thi Ngoc, Son, Nguyen Thai, Nhung, Nguyen Viet, Anh, Dang Duc, Anne-Laure, Bañuls, Van Anh, Nguyen Thi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658769/
https://www.ncbi.nlm.nih.gov/pubmed/29018250
http://dx.doi.org/10.1038/emi.2017.73