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scDual-Seq: mapping the gene regulatory program of Salmonella infection by host and pathogen single-cell RNA-sequencing

The interaction between a pathogen and a host is a highly dynamic process in which both agents activate complex programs. Here, we introduce a single-cell RNA-sequencing method, scDual-Seq, that simultaneously captures both host and pathogen transcriptomes. We use it to study the process of infectio...

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Detalles Bibliográficos
Autores principales: Avital, Gal, Avraham, Roi, Fan, Amy, Hashimshony, Tamar, Hung, Deborah T., Yanai, Itai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658913/
https://www.ncbi.nlm.nih.gov/pubmed/29073931
http://dx.doi.org/10.1186/s13059-017-1340-x