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Sirtinol regulates the balance of Th17/Treg to prevent allograft rejection
BACKGROUND: Current immunosuppressive medications used after transplantation induce significant toxicity , and a new medication regimen is needed. Based on recent research, Sirt1 exerts a proinflammatory effect on the immune response. Sirtinol is a Sirt1 inhibitor, but its impact on allograft reject...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658927/ https://www.ncbi.nlm.nih.gov/pubmed/29090089 http://dx.doi.org/10.1186/s13578-017-0182-2 |