Statistical methods to derive efficacy estimates of anti-malarials for uncomplicated Plasmodium falciparum malaria: pitfalls and challenges

The Kaplan–Meier (K–M) method is currently the preferred approach to derive an efficacy estimate from anti-malarial trial data. In this approach event times are assumed to be continuous and estimates are generated on the assumption that there is only one cause of failure. In reality, failures are ca...

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Detalles Bibliográficos
Autores principales: Dahal, Prabin, Simpson, Julie A., Dorsey, Grant, Guérin, Philippe J., Price, Ric N., Stepniewska, Kasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658934/
https://www.ncbi.nlm.nih.gov/pubmed/29073901
http://dx.doi.org/10.1186/s12936-017-2074-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658934/
https://www.ncbi.nlm.nih.gov/pubmed/29073901
http://dx.doi.org/10.1186/s12936-017-2074-7

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