Detecting the tipping points in a three-state model of complex diseases by temporal differential networks

BACKGROUND: The progression of complex diseases, such as diabetes and cancer, is generally a nonlinear process with three stages, i.e., normal state, pre-disease state, and disease state, where the pre-disease state is a critical state or tipping point immediately preceding the disease state. Tradit...

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Detalles Bibliográficos
Autores principales: Chen, Pei, Li, Yongjun, Liu, Xiaoping, Liu, Rui, Chen, Luonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658963/
https://www.ncbi.nlm.nih.gov/pubmed/29073904
http://dx.doi.org/10.1186/s12967-017-1320-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658963/
https://www.ncbi.nlm.nih.gov/pubmed/29073904
http://dx.doi.org/10.1186/s12967-017-1320-7

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