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Unique amplification of BCR-ABL1 gene fusion in a case of T-cell acute lymphoblastic leukemia

BACKGROUND: ABL1 gene translocations can be seen in precursor T-acute lymphoblastic leukemia (T-ALL). The typical translocation partner is the NUP214 gene. BCR-ABL translocations are relatively rare in this entity. Furthermore, while there have been unique patterns of amplification noted among the N...

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Detalles Bibliográficos
Autores principales: Koka, Rima, Bade, Najeebah A., Sausville, Edward A., Ning, Yi, Zou, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658965/
https://www.ncbi.nlm.nih.gov/pubmed/29093755
http://dx.doi.org/10.1186/s13039-017-0340-6