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Chemical Synthesis of the Highly Hydrophobic Antiviral Membrane‐Associated Protein IFITM3 and Modified Variants

Interferon‐induced transmembrane protein 3 (IFITM3) is an antiviral transmembrane protein that is thought to serve as the primary factor for inhibiting the replication of a large number of viruses, including West Nile virus, Dengue virus, Ebola virus, and Zika virus. Production of this 14.5 kDa, 133...

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Detalles Bibliográficos
Autores principales: Harmand, Thibault J., Pattabiraman, Vijaya R., Bode, Jeffrey W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5658968/
https://www.ncbi.nlm.nih.gov/pubmed/28834009
http://dx.doi.org/10.1002/anie.201707554