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Endothelin A receptor blocker and calcimimetic in the adenine rat model of chronic renal insufficiency

BACKGROUND: We studied whether endothelin receptor antagonist and calcimimetic treatments influence renal damage and kidney renin-angiotensin (RA) components in adenine-induced chronic renal insufficiency (CRI). METHODS: Male Wistar rats (n = 80) were divided into 5 groups for 12 weeks: control (n =...

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Detalles Bibliográficos
Autores principales: Törmänen, Suvi, Pörsti, Ilkka, Lakkisto, Päivi, Tikkanen, Ilkka, Niemelä, Onni, Paavonen, Timo, Mustonen, Jukka, Eräranta, Arttu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659028/
https://www.ncbi.nlm.nih.gov/pubmed/29078759
http://dx.doi.org/10.1186/s12882-017-0742-z