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Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture

BACKGROUND: Neurons are highly polarized cells consisting of three distinct functional domains: the cell body (and associated dendrites), the axon and the synapse. Previously, it was believed that the clinical phenotypes of neurodegenerative diseases were caused by the loss of entire neurons, howeve...

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Detalles Bibliográficos
Autores principales: Graham, Laura C., Eaton, Samantha L., Brunton, Paula J., Atrih, Abdelmadjid, Smith, Colin, Lamont, Douglas J., Gillingwater, Thomas H., Pennetta, Giuseppa, Skehel, Paul, Wishart, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659037/
https://www.ncbi.nlm.nih.gov/pubmed/29078798
http://dx.doi.org/10.1186/s13024-017-0221-9