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Proteomic profiling of neuronal mitochondria reveals modulators of synaptic architecture
BACKGROUND: Neurons are highly polarized cells consisting of three distinct functional domains: the cell body (and associated dendrites), the axon and the synapse. Previously, it was believed that the clinical phenotypes of neurodegenerative diseases were caused by the loss of entire neurons, howeve...
Autores principales: | Graham, Laura C., Eaton, Samantha L., Brunton, Paula J., Atrih, Abdelmadjid, Smith, Colin, Lamont, Douglas J., Gillingwater, Thomas H., Pennetta, Giuseppa, Skehel, Paul, Wishart, Thomas M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659037/ https://www.ncbi.nlm.nih.gov/pubmed/29078798 http://dx.doi.org/10.1186/s13024-017-0221-9 |
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