Cargando…
Can acyclic conformational control be achieved via a sulfur–fluorine gauche effect?
The gauche conformation of the 1,2-difluoroethane motif is known to involve stabilising hyperconjugative interactions between donor (bonding, σ(C–H)) and acceptor (antibonding, σ*C–F) orbitals. This model rationalises the generic conformational preference of F–C(β)–C(α)–X systems (φ(FCCX) ≈ 60°), wh...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659174/ https://www.ncbi.nlm.nih.gov/pubmed/29511517 http://dx.doi.org/10.1039/c5sc00871a |