Identification of lineage-specifying cytokines that signal all CD8-cytotoxic lineage fate decisions in the thymus

T cell antigen receptor (TCR) signaling in the thymus initiates positive selection but CD8 lineage fate is thought to be induced by cytokines after TCR signaling has ceased, although this remains controversial and unproven. We now identify four non-common gamma chain (γc) receptor-signaling cytokine...

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Detalles Bibliográficos
Autores principales: Etzensperger, Ruth, Kadakia, Tejas, Tai, Xuguang, Alag, Amala, Guinter, Terry I., Egawa, Takeshi, Erman, Batu, Singer, Alfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659273/
https://www.ncbi.nlm.nih.gov/pubmed/28945245
http://dx.doi.org/10.1038/ni.3847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659273/
https://www.ncbi.nlm.nih.gov/pubmed/28945245
http://dx.doi.org/10.1038/ni.3847

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