Cargando…

The G-308A variant of the Tumor Necrosis Factor-α (TNF-α) gene is not associated with obesity, insulin resistance and body fat distribution

BACKGROUND: Tumor Necrosis Factor-α (TNF-α) has been implicated in the pathogenesis of insulin resistance and obesity. The increased expression of TNF-α in adipose tissue has been shown to induce insulin resistance, and a polymorphism at position -308 in the promoter region ofTNF-α has been shown to...

Descripción completa

Detalles Bibliográficos
Autores principales: Romeo, Stefano, Sentinelli, Federica, Capici, Francesca, Arca, Marcello, Berni, Andrea, Vecci, Elio, Di Mario, Umberto, Baroni, Marco Giorgio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC56593/
https://www.ncbi.nlm.nih.gov/pubmed/11570978
http://dx.doi.org/10.1186/1471-2350-2-10