Recurrent noncoding regulatory mutations in pancreatic ductal adenocarcinoma

The contributions of coding mutations to tumorigenesis are relatively well known; however, little is known about somatic alterations in noncoding DNA. Here we describe GECCO (Genomic Enrichment Computational Clustering Operation) to analyze somatic noncoding alterations in 308 pancreatic ductal aden...

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Detalles Bibliográficos
Autores principales: Feigin, Michael E., Garvin, Tyler, Bailey, Peter, Waddell, Nicola, Chang, David K., Kelley, David R., Shuai, Shimin, Gallinger, Steven, McPherson, John D., Grimmond, Sean M., Khurana, Ekta, Stein, Lincoln D., Biankin, Andrew V., Schatz, Michael C., Tuveson, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659388/
https://www.ncbi.nlm.nih.gov/pubmed/28481342
http://dx.doi.org/10.1038/ng.3861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659388/
https://www.ncbi.nlm.nih.gov/pubmed/28481342
http://dx.doi.org/10.1038/ng.3861

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