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RNA N(6)-adenosine methylation (m(6)A) steers epitranscriptomic control of herpesvirus replication
Latency is a hallmark of all herpesviruses, during which the viral genomes are silenced through DNA methylation and suppressive histone modifications. When latent herpesviruses reactivate to undergo productive lytic replication, the suppressive epigenetic marks are replaced with active ones to allow...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659614/ https://www.ncbi.nlm.nih.gov/pubmed/29082271 |