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Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice

The increased prevalence of obesity and its cardiometabolic implications demonstrates the imperative to identify novel therapeutic targets able to effect meaningful metabolic changes in this population. Antibody-mediated targeting of fibroblast growth factor receptor 1c isoform (FGFR1c) has been sho...

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Detalles Bibliográficos
Autores principales: Lewis, Jo E., Samms, Ricardo J., Cooper, Scott, Luckett, Jeni C., Perkins, Alan C., Dunbar, James D., Smith, Dennis P., Emmerson, Paul J., Adams, Andrew C., Ebling, Francis J. P., Tsintzas, Kostas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659699/
https://www.ncbi.nlm.nih.gov/pubmed/28938451
http://dx.doi.org/10.1210/en.2017-00591