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Optogenetic Analysis of Depolarization-Dependent Glucagonlike Peptide-1 Release

Incretin hormones play an important role in the regulation of food intake and glucose homeostasis. Glucagonlike peptide-1 (GLP-1)–secreting cells have been demonstrated to be electrically excitable and to fire action potentials (APs) with increased frequency in response to nutrient exposure. However...

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Detalles Bibliográficos
Autores principales: Chimerel, Catalin, Riccio, Cristian, Murison, Keir, Gribble, Fiona M., Reimann, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659701/
https://www.ncbi.nlm.nih.gov/pubmed/28938466
http://dx.doi.org/10.1210/en.2017-00434