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Protein synthesis inhibition enhances paraptotic death induced by inhibition of cyclophilins in glioblastoma cells

Treatment of cancer is frequently unsuccessful related to the loss of apoptotic signaling in malignant cells. This is a particular problem for high-grade gliomas, such as Glioblastoma Multiforme (GBM), which are almost universally fatal within a year or so of diagnosis. Novel therapies that capitali...

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Detalles Bibliográficos
Autores principales: Wang, Lin, Gundelach, Justin H, Bram, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659709/
https://www.ncbi.nlm.nih.gov/pubmed/29085850