DNA methylation and gene expression of TXNIP in adult offspring of women with diabetes in pregnancy

BACKGROUND: Fetal exposure to maternal diabetes increases the risk of type 2 diabetes (T2DM), possibly mediated by epigenetic mechanisms. Low blood TXNIP DNA methylation has been associated with elevated glucose levels and risk of T2DM, and increased skeletal muscle TXNIP gene expression was reporte...

Descripción completa

Detalles Bibliográficos
Autores principales: Houshmand-Oeregaard, Azadeh, Hjort, Line, Kelstrup, Louise, Hansen, Ninna S., Broholm, Christa, Gillberg, Linn, Clausen, Tine D., Mathiesen, Elisabeth R., Damm, Peter, Vaag, Allan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659766/
https://www.ncbi.nlm.nih.gov/pubmed/29077742
http://dx.doi.org/10.1371/journal.pone.0187038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659766/
https://www.ncbi.nlm.nih.gov/pubmed/29077742
http://dx.doi.org/10.1371/journal.pone.0187038

Ejemplares similares