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Enhanced chromatin accessibility of the dosage compensated Drosophila male X-chromosome requires the CLAMP zinc finger protein

The essential process of dosage compensation is required to equalize gene expression of X-chromosome genes between males (XY) and females (XX). In Drosophila, the conserved Male-specific lethal (MSL) histone acetyltransferase complex mediates dosage compensation by increasing transcript levels from...

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Detalles Bibliográficos
Autores principales: Urban, Jennifer, Kuzu, Guray, Bowman, Sarah, Scruggs, Benjamin, Henriques, Telmo, Kingston, Robert, Adelman, Karen, Tolstorukov, Michael, Larschan, Erica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659772/
https://www.ncbi.nlm.nih.gov/pubmed/29077765
http://dx.doi.org/10.1371/journal.pone.0186855