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Correlated receptor transport processes buffer single-cell heterogeneity

Cells typically vary in their response to extracellular ligands. Receptor transport processes modulate ligand-receptor induced signal transduction and impact the variability in cellular responses. Here, we quantitatively characterized cellular variability in erythropoietin receptor (EpoR) traffickin...

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Detalles Bibliográficos
Autores principales: Kallenberger, Stefan M., Unger, Anne L., Legewie, Stefan, Lymperopoulos, Konstantinos, Klingmüller, Ursula, Eils, Roland, Herten, Dirk-Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659801/
https://www.ncbi.nlm.nih.gov/pubmed/28945754
http://dx.doi.org/10.1371/journal.pcbi.1005779