Anti‐atherosclerotic effect of the angiotensin 1–7 mimetic AVE0991 is mediated by inhibition of perivascular and plaque inflammation in early atherosclerosis

BACKGROUND AND PURPOSE: Inflammation plays a key role in atherosclerosis. The protective role of angiotensin 1–7 (Ang‐(1–7)) in vascular pathologies suggested the therapeutic use of low MW, non‐peptide Ang‐(1–7) mimetics, such as AVE0991. The mechanisms underlying the vaso‐protective effects of AVE0...

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Detalles Bibliográficos
Autores principales: Skiba, D S, Nosalski, R, Mikolajczyk, T P, Siedlinski, M, Rios, F J, Montezano, A C, Jawien, J, Olszanecki, R, Korbut, R, Czesnikiewicz‐Guzik, M, Touyz, R M, Guzik, T J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Themed Section: Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659999/
https://www.ncbi.nlm.nih.gov/pubmed/27935022
http://dx.doi.org/10.1111/bph.13685

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5659999/
https://www.ncbi.nlm.nih.gov/pubmed/27935022
http://dx.doi.org/10.1111/bph.13685

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