Safety, pharmacokinetics, metabolism and radiation dosimetry of (18)F-tetrafluoroborate ((18)F-TFB) in healthy human subjects

BACKGROUND: (18)F-Tetrafluoroborate ((18)F-TFB) is a promising iodide analog for PET imaging of thyroid cancer and sodium/iodide symporter (NIS) reporter activity in viral therapy applications. The aim of this study was to evaluate the safety, pharmacokinetics, biodistribution, and radiation dosimet...

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Detalles Bibliográficos
Autores principales: Jiang, Huailei, Schmit, Nicholas R., Koenen, Alex R., Bansal, Aditya, Pandey, Mukesh K., Glynn, Robert B., Kemp, Bradley J., Delaney, Kera L., Dispenzieri, Angela, Bakkum-Gamez, Jamie N., Peng, Kah-Whye, Russell, Stephen J., Gunderson, Tina M., Lowe, Val J., DeGrado, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660009/
https://www.ncbi.nlm.nih.gov/pubmed/29080017
http://dx.doi.org/10.1186/s13550-017-0337-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660009/
https://www.ncbi.nlm.nih.gov/pubmed/29080017
http://dx.doi.org/10.1186/s13550-017-0337-5

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