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Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior

Perturbed neuronal migration and circuit development have been implicated in the pathogenesis of neurodevelopmental diseases; however, the direct steps linking these developmental errors to behavior alterations remain unknown. Here we demonstrate that Wnt/C-Kit signaling is a key regulator of glia-g...

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Detalles Bibliográficos
Autores principales: Bocchi, Riccardo, Egervari, Kristof, Carol-Perdiguer, Laura, Viale, Beatrice, Quairiaux, Charles, De Roo, Mathias, Boitard, Michael, Oskouie, Suzanne, Salmon, Patrick, Kiss, Jozsef Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660087/
https://www.ncbi.nlm.nih.gov/pubmed/29079819
http://dx.doi.org/10.1038/s41467-017-01046-w