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Hemodynamic and Pathologic Characterization of the TASK-1(−/−) Mouse Does Not Demonstrate Pulmonary Hypertension
INTRODUCTION: Pulmonary hypertension (PH) carries significant associated morbidity and mortality and the underlying molecular mechanisms of PH are not well understood. Loss-of-function mutations in TASK-1 potassium channels are associated with PH in humans. Although TASK-1 has been considered in the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660113/ https://www.ncbi.nlm.nih.gov/pubmed/29109948 http://dx.doi.org/10.3389/fmed.2017.00177 |