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miR-1199-5p and Zeb1 function in a double-negative feedback loop potentially coordinating EMT and tumour metastasis

Epithelial tumour cells can gain invasive and metastatic capabilities by undergoing an epithelial–mesenchymal transition. Transcriptional regulators and post-transcriptional effectors like microRNAs orchestrate this process of high cellular plasticity and its malignant consequences. Here, using micr...

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Detalles Bibliográficos
Autores principales:	Diepenbruck, Maren, Tiede, Stefanie, Saxena, Meera, Ivanek, Robert, Kalathur, Ravi Kiran Reddy, Lüönd, Fabiana, Meyer-Schaller, Nathalie, Christofori, Gerhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660124/ https://www.ncbi.nlm.nih.gov/pubmed/29079737 http://dx.doi.org/10.1038/s41467-017-01197-w

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