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A genomic screen for angiosuppressor genes in the tumor endothelium identifies a multifaceted angiostatic role for bromodomain containing 7 (BRD7)

Tumor angiogenesis is characterized by deregulated gene expression in endothelial cells (EC). While studies until now have mainly focused on overexpressed genes in tumor endothelium, we here describe the identification of transcripts that are repressed in tumor endothelium and thus have potential su...

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Detalles Bibliográficos
Autores principales: van Beijnum, Judy R., Nowak-Sliwinska, Patrycja, van Berkel, Maaike, Wong, Tse J., Griffioen, Arjan W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660147/
https://www.ncbi.nlm.nih.gov/pubmed/28951988
http://dx.doi.org/10.1007/s10456-017-9576-3