Oligomerization and ATP stimulate condensin-mediated DNA compaction

Large-scale chromatin remodeling during mitosis is catalyzed by a heteropentameric enzyme known as condensin. The DNA-organizing mechanism of condensin depends on the energy of ATP hydrolysis but how this activity specifically promotes proper compaction and segregation of chromosomes during mitosis...

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Detalles Bibliográficos
Autores principales: Keenholtz, Ross A., Dhanaraman, Thillaivillalan, Palou, Roger, Yu, Jia, D’Amours, Damien, Marko, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660149/
https://www.ncbi.nlm.nih.gov/pubmed/29079757
http://dx.doi.org/10.1038/s41598-017-14701-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660149/
https://www.ncbi.nlm.nih.gov/pubmed/29079757
http://dx.doi.org/10.1038/s41598-017-14701-5

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