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Oligomerization and ATP stimulate condensin-mediated DNA compaction
Large-scale chromatin remodeling during mitosis is catalyzed by a heteropentameric enzyme known as condensin. The DNA-organizing mechanism of condensin depends on the energy of ATP hydrolysis but how this activity specifically promotes proper compaction and segregation of chromosomes during mitosis...
Autores principales: | Keenholtz, Ross A., Dhanaraman, Thillaivillalan, Palou, Roger, Yu, Jia, D’Amours, Damien, Marko, John F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660149/ https://www.ncbi.nlm.nih.gov/pubmed/29079757 http://dx.doi.org/10.1038/s41598-017-14701-5 |
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