Functionalization of microparticles with mineral coatings enhances non-viral transfection of primary human cells

Gene delivery to primary human cells is a technology of critical interest to both life science research and therapeutic applications. However, poor efficiencies in gene transfer and undesirable safety profiles remain key limitations in advancing this technology. Here, we describe a materials-based a...

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Detalles Bibliográficos
Autores principales: Khalil, Andrew S., Yu, Xiaohua, Xie, Angela W., Fontana, Gianluca, Umhoefer, Jennifer M., Johnson, Hunter J., Hookway, Tracy A., McDevitt, Todd C., Murphy, William L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660152/
https://www.ncbi.nlm.nih.gov/pubmed/29079806
http://dx.doi.org/10.1038/s41598-017-14153-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660152/
https://www.ncbi.nlm.nih.gov/pubmed/29079806
http://dx.doi.org/10.1038/s41598-017-14153-x

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