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Male fertility restored by transplanting primordial germ cells into testes: a new way towards efficient transgenesis in chicken

The ongoing progress in primordial germ cell derivation and cultivation is opening new ways in reproductive biotechnology. This study tested whether functional sperm cells can be matured from genetically manipulated primordial germ cells after transplantation in adult testes and used to restore fert...

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Detalles Bibliográficos
Autores principales: Trefil, Pavel, Aumann, Dorothea, Koslová, Anna, Mucksová, Jitka, Benešová, Barbora, Kalina, Jiří, Wurmser, Christine, Fries, Ruedi, Elleder, Daniel, Schusser, Benjamin, Hejnar, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660165/
https://www.ncbi.nlm.nih.gov/pubmed/29079843
http://dx.doi.org/10.1038/s41598-017-14475-w