Somatic mutation driven codon transition bias in human cancer

Accumulation of DNA mutations alters amino acid sequence in the key domains of oncoproteins, leading to cellular malignant transformation. Due to redundancy of the genetic code, the same amino acid alteration can be achieved by multiple distinct genetic mutations, which are considered functionally i...

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Detalles Bibliográficos
Autores principales: Son, Hyeonju, Kang, Hyundeok, Kim, Hyun Seok, Kim, Sangwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660177/
https://www.ncbi.nlm.nih.gov/pubmed/29079855
http://dx.doi.org/10.1038/s41598-017-14543-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660177/
https://www.ncbi.nlm.nih.gov/pubmed/29079855
http://dx.doi.org/10.1038/s41598-017-14543-1

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