Involvement of ER stress, PI3K/AKT activation, and lung fibroblast proliferation in bleomycin-induced pulmonary fibrosis

Pulmonary fibrosis is characterized by fibroblast proliferation and extracellular matrix remodelling, leading to respiratory insufficiency. The mechanisms underlying this progressive and devastating disease remain unclear. Conditions that can impair the function of the endoplasmic reticulum (ER) cau...

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Detalles Bibliográficos
Autores principales: Hsu, Han-Shui, Liu, Chen-Chi, Lin, Jiun-Han, Hsu, Tien-Wei, Hsu, Jyuan-Wei, Su, Kelly, Hung, Shih-Chieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660192/
https://www.ncbi.nlm.nih.gov/pubmed/29079731
http://dx.doi.org/10.1038/s41598-017-14612-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660192/
https://www.ncbi.nlm.nih.gov/pubmed/29079731
http://dx.doi.org/10.1038/s41598-017-14612-5

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