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Impact of intracellular glyceraldehyde-derived advanced glycation end-products on human hepatocyte cell death

Hepatocyte cell death is a key feature of nonalcoholic steatohepatitis (NASH); however, the pathogenesis of NASH currently remains unclear. We aimed to investigate the effects of intracellular glyceraldehyde (GA)-derived advanced glycation end-products (GA-AGEs) on human hepatocyte cell death. The a...

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Detalles Bibliográficos
Autores principales: Sakasai-Sakai, Akiko, Takata, Takanobu, Takino, Jun-ichi, Takeuchi, Masayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660208/
https://www.ncbi.nlm.nih.gov/pubmed/29079763
http://dx.doi.org/10.1038/s41598-017-14711-3