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Dual Biomembrane Force Probe enables single-cell mechanical analysis of signal crosstalk between multiple molecular species

Conventional approaches for studying receptor-mediated cell signaling, such as the western blot and flow cytometry, are limited in three aspects: 1) The perturbing preparation procedures often alter the molecules from their native state on the cell; 2) Long processing time before the final readout m...

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Detalles Bibliográficos
Autores principales: Ju, Lining, Chen, Yunfeng, Li, Kaitao, Yuan, Zhou, Liu, Baoyu, Jackson, Shaun P., Zhu, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5660210/
https://www.ncbi.nlm.nih.gov/pubmed/29079742
http://dx.doi.org/10.1038/s41598-017-13793-3